Publications from the Hidalgo lab   

 

Hidalgo, A and Logan, A (2017) Go and Stop signals for glial regeneration.

CURRENT OPINION IN NEUROBIOLOGY, 47: 182-187


Ulian-Benitez S., Bishop S., Foldi I., Wentzell J., Okenwa C., Forero MG., Zhu B., Moreira M., Phizaclea M., McIlroy G., Li G., Gay N., Hidalgo A. (2017) Kek-6: a truncated Trk-like receptor for Drosophila neurotrophin-2 regulates structural synaptic plasticity.

PLOS GENETICS  doi.org/10.1371/journal.pgen.1006968


Kato K., Losada-Perez M and Hidalgo A (2017) The gene network underlying the glial regenerative response to central nervous system injury. DEVELOPMENTAL DYNAMICS DOI: 10.10002/dvdy.24565


Foldi I, Anthoney N, Harrison N, Gangloff M, Verstak B, Ponnadai Nallasivan M, AlAhmed S, Zhu B, Phizacklea M, Losada-Perez M, Moreira M, Gay NJ, Hidalgo A (2017) Three-tier regulation of cell number plasticity by neurotrophins and Tolls in Drosophila 

JOURNAL OF CELL BIOLOGY 216 (5) 1421-1438; DOI: 10.1083/jcb.201607098

  1. Bullet                  Selected by J Cell Biology as “One of the Top 10 articles published in 2017”

  2. Bullet                  See highlight pre-view dedicated to our article:

                      Austin B. Keeler, Christopher D. Deppmann  (2017) The evolutionary origins of antagonistic neurotrophin signaling.

                      JOURNAL OF CELL BIOLOGY 216 (5) 1223-1225; DOI: 10.1083/jcb.201702115


Losada-Perez M, Harrison N and Hidalgo, A (2017) Glial kon/NG2 gene network for central nervous system repair. 

NEURAL REGENERATION RESEARCH 12, 31-34

Losada-Perez M, Harrison N, Hidalgo A (2016) Molecular mechanism of central nervous system repair by the Drosophila NG2 homologue kon-tiki. JOURNAL OF CELL BIOLOGY 214 (5) 587-601; DOI: 10.1083/jcb.201603054

Kato K, Konno D, Berry M, Matsuzaki F, Logan A and Hidalgo A (2015) Prox1 inhibits proliferation and is required for differentiation of the oligodendrocyte cell lineage in the mouse. PLoS ONE 10(12): e0145334. DOI: 10.1371/journal.pone.0145334

Sutcliffe B, Forero MG, Zhu B, Robinson I and Hidalgo A (2013) Neuron-type specific functions of DNT1, DNT2 and Spz at the Drosophila neuromuscular junction. PLoS ONE 8(10): e75902. doi:10.1371/journal.pone.0075902


McIlroy G, Foldi I, Aurikko J, Wentzell JS, Lim MA, Fenton JC, Gay NJ and Hidalgo A (2013) Toll-6 and Toll-7 function as neurotrophin receptors in the Drosophila melanogaster CNS.

NATURE NEUROSCIENCE 16, 1248-1256. doi: 10.1038/nn.3474.                                                                                                                    

  1. Bullet                 Recommended by Faculty of 1000 http://f1000.com/prime/718049779?bd=1&ui=21597


Kato and Hidalgo (2013) An injury paradigm to investigate central nervous system repair in Drosophila.

JOVE 73, e50306, doi: 10.3791/50306


Forero, Kato and Hidalgo (2012) Automatic cell counting in vivo in the larval nervous system of Drosophila. 

J MICROSCOPY 246(2):202-12. doi: 10.1111/j.1365-2818.2012.03608


Kato, Forero, Fenton and Hidalgo (2011) The glial regenerative to CNS injury is enabled by Pros-Notch and Pros-NFkB feedback. 

PLoS BIOLOGY 9, e1001133


  1. Bullet               See Editor’s Highlight dedicated to our article:  PLoS Biology 9(8): e1001136 https://doi.org/10.1371/journal.pbio.1001136


Forero and Hidalgo (2011) Image processing methods for automatic cell counting in vivo or in situ using 3D confocal microscopy. In

“ADVANCED BIOMEDICAL ENGINEERING” Ed. G.D.Gargiulo and A.McEwan.Intech Open Access Publisher, pages 183-204


Hidalgo, Kato, Sutcliffe, McIlroy, Bishop and AlAhmed (2011) Trophic neuron-glia interactions and cell number adjustments in the fruit fly.

GLIA DOI: 10.1002/glia.21092

Forero, Learte, Cartwright and Hidalgo (2010) DeadEasy MitoGlia: automatic counting of mitotic cells and glia in the central nervous system of Drosophila.

PLoS ONE 5, e10557 

Forero, Pennack, and Hidalgo (2010) DeadEasy neurons: Automatic counting of HB9 neuronal nuclei in Drosophila.

CYTOMETRY PART A 77A, 371-378

Forero MG, Pennack JA, Learte AR and Hidalgo A (2009) DeadEasy Caspase: automatic counting of apoptotic cells in Drosophila.                                                         PLoS ONE 4, e5441.

Zhu B., Pennack J.A., McQuilton P., Forero M.G., Mizuguchi K., Sutcliffe B., Gu C.J., Fenton J.C. and Hidalgo A. (2008) Drosophila neurotrophins reveal a common mechanism of nervous system formation.                                                                                                                                                                                                    PLoS BIOLOGY 6(11), e284   (see also video)         

  1. Bullet               Recommended by Faculty of 1000: http://f1000.com/prime/1158489

Learte A.R., Forero M.G. and Hidalgo A. (2008) Gliatrophic and gliatropic roles of PVF/PVR signalling during axon guidance.

GLIA 56, 164-176.


Griffiths R., Benito-Sipos J., Fenton J.C., Torroja L. and Hidalgo A. (2007) Two distinct mechanisms segregate Prospero in the longitudinal glia underlying the timing of interactions with axons. 

NEURON-GLIA BIOLOGY 2, 75-88.


Learte A.R. and Hidalgo, A. (2007) The role of glial cells in axon guidance, fasciculation and targeting. In

“AXON GROWTH AND GUIDANCE” Ed. Dominique Bagnard, Landes Biosciences.


Hidalgo A., Learte A.R., McQuilton P., Pennack J. and Zhu B.(2006) Gliatrophic and neurotrophic contexts in Drosophila.

BRAIN, BEHAVIOUR AND EVOLUTION 68, 173-180.


Hidalgo A. and Griffiths R. (2004) Coupling glial numbers to axonal patterns.

CELL CYCLE 3, 1118-1120.


Griffiths R. and Hidalgo A. (2004) Prospero maintains the mitotic potential of glial precursors enabling them to respond to neurons.                                                       EMBO JOURNAL 23, 2440-2450.

Kinrade E. and Hidalgo A. (2004) Lateral neuron-glia interactions steer the response of axons to the robo code.                                                                               NEURON-GLIA BIOLOGY 1, 101-112.


Hidalgo A. and ffrench-Constact C. (2003) The control of cell number during central nervous system development in flies and mice.

MECHANISMS OF DEVELOPMENT, Special Issue 120, 1311-1325.


Hidalgo A. (2003) Neuron-glia interactions during axon guidance.

TRANS BIOCHEM SOC. 31, 50-55.


Hidalgo A. (2002) Interactive nervous system development: control of cell survival in Drosophila.

TRENDS IN NEUROSCIENCES 25, 365-370.

Hidalgo A., Kinrade E. and Georgiou M. (2001) The Drosophila neuregulin Vein maintains glial survival during axon guidance in the CNS.                            DEVELOPMENTAL CELL 1, 679-690.

  1. Bullet                   See mini-review dedicated to our findings: Beck and Fainzilber (2002) Neuron 33, 673-675

  2. Bullet                   See mini-review dedicated to our findings: Leslie (2001) Journal of Cell BIology 155, 871

Kinrade E., Brates T., Tear G. and Hidalgo A.(2001)  Roundabout signalling, cell contact and trophic support confine longitudinal glia and axons in the Drosophila CNS. DEVELOPMENT 128, 207-216.

Hidalgo A. & Booth G.E. (2000) Glia dictate pioneer axon trajectories in the Drosophila embryonic CNS.

DEVELOPMENT 127, 393-402

Booth G.E., Kinrade E. and Hidalgo A. (2000) Glia maintain follower neuron survival during Drosophila CNS development.                                                      DEVELOPMENT  127, 237-244.

  1. Bullet                  See review dedicated to our findings: Shepherd D (2000) BioEssays 22, 407-9

Sweeney S.T., Hidalgo A., deBelle J.S. and Keishishian H. (2000) Functional Cell Ablation . In                                                                                                    "DROSOPHILA PROTOCOLS "  Eds Sullivan, W., Ashburner M., and Hawley,R.S. Cold Spring Harbour Press, New York, 449-477.

Hidalgo A. (1998) Wing patterning knot untangled.

BIOESSAYS 20, 449-452.


Hidalgo A. (1998) Growth and patterning from the engrailed interface.

INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY 42, 317-324.


Hidalgo A. and Brand A.H. (1997) Targeted neuronal ablation: the role of pioneer neurons in guidance and fasciculation in the CNS of Drosophila.

DEVELOPMENT 124, 3253-3262.


Hidalgo A. (1996) The roles of engrailed.

TRENDS IN GENETICS 12, 1-4.


Hidalgo A., Urban J. and Brand A.H. (1995) Targeted ablation of glia disrupts axon tract formation in the Drosophila CNS.

DEVELOPMENT 121, 3703-3712.


Hidalgo A. (1994) Three distinct roles for the engrailed gene in Drosophila wing development.

CURRENT BIOLOGY 4, 1087-1098.


Ingham P. and Hidalgo A. (1993) Regulation of wingless transcription in the Drosophila embryo.

DEVELOPMENT 117, 283-291.


Hidalgo A. (1991). Interactions between segment polarity genes and the generation of the segmental pattern in Drosophila.

MECHANISMS OF DEVELOPMENT 35, 77-87.


Hidalgo A. and Ingham P.W. (1990). Cell patterning in Drosophila: spatial regulation of the segment polarity gene patched.

DEVELOPMENT 110, 291-302.


Ingham P.W., Hidalgo A. and Taylor A.M. (1990). Advantages and limitations of in situ hybridisation as exemplified by the molecular genetic analysis of Drosophila development. In:

“In situ hybridisation: application to developmental biology and medicine”. Ed. N Harris and DG Wilkinson. Society for Experimental Biology, Seminar Series 40, Cambridge University Press, 97-114.


Nakano Y., Guerrero I., Hidalgo A., Taylor A., Whittle J.R.S. and Ingham P.W. (1989) The Drosophila segment polarity gene patched encodes a protein with multiple potential membrane spanning domains.

NATURE 341, 508-513.


Kessling AM, Taylor R, Temple A, Hutson J, Hidalgo A, Humphries SE. (1988) A PvuII polymorphism in the 5' flanking region of the apolipoprotein AIV gene: its use to study genetic variation determining serum lipid and apolipoprotein concentration.

HUMAN GENETICS  78(3):237-9.