Current Major Research Interests:


Interaction of HSPGs with neuroregulatory growth factors
and their receptors

Novel strategies for sequence analysis of HS

Creation and screening of bioactive HS saccharide libraries

HS in neural development (structure and biosynthesis)

HS sulphotransferases

HS in model organisms – C elegans and Drosophila

HS in neural diseases (interactions with proteins involved in Alzheimers and Prion diseases)


Current work in the lab is funded by grants from the MRC, BBSRC, EU, HFSP and GlaxoSmithKline, and their generous support is gratefully acknowledged.

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