Emma Sisley

Emma Sisley, mass spectrometrist

I am a PhD student from the Sci-Phy doctoral training programme. My project will develop new analytical techniques to improve our understanding of the pathogenesis of fibrosis. The overall aim is to develop and apply liquid extraction surface analysis (LESA) mass spectrometry (MS) to kidney tissue samples to study the pathogenesis of renal fibrosis. This will include new physical science techniques such as a LESA MS imaging protocol for bottom-up analysis of tissue and fusing LESA MS images with histology images to improve spatial resolution. The project contributes to the UK healthcare challenge 'Rebuilding the ageing and diseased body', and will be carried out in collaboration with the multinational biopharmaceutical company UCB.



  1. J.R.N. Haler, E.K. Sisley, Y.L. Cintron-Diaz, S.N. Meitei, H.J. Cooper and F. Fernandez-Lima. Workflow for fast lipid tissue screening using LESA-FT-ICR-MS. Analytical Methods, 2385-2395.


  1. R.L. Griffiths, E.K. Sisley, A.F. Lopez-Clavijo, A.L. Simmonds, I.B. Styles and H.J. Cooper. Native mass spectrometry imaging of intact proteins and protein complexes in thin tissue sections. International Journal of Mass Spectrometry, 23-29.